A community for students.

Here's the question you clicked on:

55 members online
  • 0 replying
  • 0 viewing

anonymous

  • 5 years ago

p53 in the Cell Cycle...

  • This Question is Closed
  1. tim
    • 5 years ago
    Best Response
    You've already chosen the best response.
    Medals 0

    is a protein that functions to block the cell cycle if the DNA is damaged. If the damage is severe this protein can cause apoptosis (cell death). p53 levels are increased in damaged cells. This allows time to repair DNA by blocking the cell cycle. A p53 mutation is the most frequent mutation leading to cancer. An extreme case of this is Li Fraumeni syndrome, where a genetic a defect in p53 leads to a high frequency of cancer in affected individuals.

  2. anonymous
    • 5 years ago
    Best Response
    You've already chosen the best response.
    Medals 0

    p53 is known as tumor suppersor gene coz of the above mentioned reasons by the tim

  3. anonymous
    • 5 years ago
    Best Response
    You've already chosen the best response.
    Medals 0

    lack of nucleotide, UV radiation, ionizing radiation, oncogene signaling and hypoxia induce P53 expression, then P53 proteins cause cell cycle arrest, DNA repair, block of angiogenesis and apoptosis, so it is needed to block unregulated cell proliferation

  4. Not the answer you are looking for?
    Search for more explanations.

    • Attachments:

Ask your own question

Sign Up
Find more explanations on OpenStudy
Privacy Policy

Your question is ready. Sign up for free to start getting answers.

spraguer (Moderator)
5 → View Detailed Profile

is replying to Can someone tell me what button the professor is hitting...

23

  • Teamwork 19 Teammate
  • Problem Solving 19 Hero
  • You have blocked this person.
  • ✔ You're a fan Checking fan status...

Thanks for being so helpful in mathematics. If you are getting quality help, make sure you spread the word about OpenStudy.

This is the testimonial you wrote.
You haven't written a testimonial for Owlfred.