Tetrodotoxin blocks voltage-gated sodium channels and ouabain blocks sodium-potassium pumps. If you added both tetrodotoxin and ouabain to a solution containing neural tissue, what responses would you expect?
a. No effect, the substances counteract each other.
b. Immediate loss of resting potential.
c. slow decrease of resting potential and action potential amplitudes.
d. immediate loss of action potential with gradual loss of resting potential
Stacey Warren - Expert brainly.com
Hey! We 've verified this expert answer for you, click below to unlock the details :)
At vero eos et accusamus et iusto odio dignissimos ducimus qui blanditiis praesentium voluptatum deleniti atque corrupti quos dolores et quas molestias excepturi sint occaecati cupiditate non provident, similique sunt in culpa qui officia deserunt mollitia animi, id est laborum et dolorum fuga.
Et harum quidem rerum facilis est et expedita distinctio. Nam libero tempore, cum soluta nobis est eligendi optio cumque nihil impedit quo minus id quod maxime placeat facere possimus, omnis voluptas assumenda est, omnis dolor repellendus.
Itaque earum rerum hic tenetur a sapiente delectus, ut aut reiciendis voluptatibus maiores alias consequatur aut perferendis doloribus asperiores repellat.
I got my questions answered at brainly.com in under 10 minutes. Go to brainly.com now for free help!
A action potential is instigated by electrolytes, in this case let's limit ourselves to Na+ & K+ . Na+ is responsible for the depolarisation, while K+ is responsible for the repolarisation, these exchanges need to occure for action potential to occure. Now we've established that a "immediate loss of action potential" will occure.
Now for resting potential, a resting potential should be at -90 mV (If and i stress IF i remember correctly.) But since since you've blocked the the sodiumpotassium pump it will gradually decay. resulting in a "Gradual loss of resting potential".
Short answer: "d. immediate loss of action potential with gradual loss of resting potential"