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With an exclamation point ("Carthago delenda est!") or a question mark ("Are you a man or a mouse?").
if you want you can end it with a conclusion or a thesis statement.
Your conclusion will very closely resemble your introduction, but it will be in the past tense.
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What type of persuasive speech are you writing? Do you have any additional details or requirements?
My personal preference for most persuasive speeches is to organize it around Monroe's Motivational Sequence. It provides a very effective framework for the whole speech including how to end it properly with a call to action. This site is a good resource for how to do it and it includes examples: http://www.sanjuan.edu/webpages/mikeberry/speech.cfm?subpage=66682
With a "call to action" basically telling the people to go and do whatever you were persuading them about.