myininaya
  • myininaya
So I know this person, not personally, but they have one green eye and one blue eye. So I guess they carry both recessive genes for blue and green, right? But is there a more dominant eye color of these recessive eye colors? Which is more likely to occur in offspring? Blue eyes? Green eyes? Or both?
Biology
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schrodinger
  • schrodinger
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hectoroftroy
  • hectoroftroy
Was this person a female, by any chance? I ask because quite a few eye color genes (there are more than 15 and of those fifteen there are many variants or alleles) are X linked, or if not located on the X chromosome then controlled by protein products of genes on the X chromosome. Cells can only live with one active X chromosome - two affects the dosages of gene products in bad (read 'lethal') ways, so in all the cell lineages that form during development, one of the two X chromosomes compacts itself into a little package and sits idly by. It is incredible that females don't wind up looking like patchworks anyway as that is what they are - it's just that one X chromosome (with the blue set of alleles) got inactivated in the cell line which gave rise to one eye and the other X chromosome (with the green set of alleles) got in the other eye.
hectoroftroy
  • hectoroftroy
And which occurs in her offspring depends on which X chromosome she passes on to them. Equal probability, I'd say. The kid with the green X would have green eyes and the kid with the blue X would have blue eyes - dependent of course on what they get from their Dad. The question is whether the odd pattern of X inactivation is itself X dependent, in which case she would be more likely to have children with mixed eye colors. And that I don't know off the top of my head but I can definitely read up on.
hectoroftroy
  • hectoroftroy
But only if those children of hers were girls. Boys only have the one X, so no inactivation occurs.

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myininaya
  • myininaya
Oh ok. So the probability of the males having these type of mixed eye color thing going on is zero?
myininaya
  • myininaya
Or close to zero?
hectoroftroy
  • hectoroftroy
If X inactivation is actually the cause of it, yes, zero. Females have two X chromosomes, but only one can be active so the other shrivels up as discussed above. Males have an X and a Y, so no need for the second (missing) X to be inactivated. Mom passes of the two X chromosomes onto all offspring. And that X will either have the blue set of genes or the green set of genes.
myininaya
  • myininaya
Ok I'm about to give you a medal. lol. Nice information hector :)
hectoroftroy
  • hectoroftroy
My pleasure. You should come to bio more often. :D
myininaya
  • myininaya
Just in case you wanted to look at this
hectoroftroy
  • hectoroftroy
Oh that's totally whacked.
hectoroftroy
  • hectoroftroy
I'll link to it in the Feedback thread so they find it.
myininaya
  • myininaya
lol but really good information on the genetic stuff. I really liked in when I took just that one biology class. We made babies with other students in the class. My family had two moms because there were too many girls in the class.
hectoroftroy
  • hectoroftroy
What a cute lab. We shook a paper bag full of alleles and made baby dragons in ours...
lgbasallote
  • lgbasallote
i wanted to know what @myininaya was talking about so...
lgbasallote
  • lgbasallote
on a related question @hectoroftroy is it possible to have a green eye AND a blue eye?
myininaya
  • myininaya
yes i seen it before
lgbasallote
  • lgbasallote
wow that's cool...having two of the coolest eye colors...i'd love to be just blue eyed though..*sigh* if only snatching eyes was legal :(
myininaya
  • myininaya
I have blue eyes :)
lgbasallote
  • lgbasallote
perfect >:))))) *hisssss*

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