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I don't know what the exam includes, but I used to be pre-pharmacy and I know that nursing requirement courses were very similar to those of pharmacy as well as those of pre-med. With that being said, I would assume that you need a good understanding of:
- Anatomy & Physiology
- 1 General Chemistry & Biochemistry (for nursing majors!)
- Math (I would guess up to about Algebra 2 since you need to know conversions well but varies for each school)
- introductory or basic pharmacology
Again, I don't know what the exam consists of but I would guess that those are some of the most important topics covered. You could always search on Bing "practice HESI A2 exam questions and topics". I am sure that there are many other people who have posted questions from previous exams in the past years that could guide you in the right direction. Best of luck! Cheers.