BRCA1 mutation BRCA2 mutation No BRCA mutation Total Number of patients 89 35 318 442 Average age at diagnosis 43.9 46.2 50.4 Preventative mastectomy* 6 3 14 23 Preventative oophorectomy* 38 7 22 67 Number of deaths 16 1 21 38 Percent died 18 2.8 6.9 8.6 *A mastectomy is the surgical removal of one or both breasts, either partially of fully. An oophorectomy is the surgical removal of an ovary or ovaries.

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BRCA1 mutation BRCA2 mutation No BRCA mutation Total Number of patients 89 35 318 442 Average age at diagnosis 43.9 46.2 50.4 Preventative mastectomy* 6 3 14 23 Preventative oophorectomy* 38 7 22 67 Number of deaths 16 1 21 38 Percent died 18 2.8 6.9 8.6 *A mastectomy is the surgical removal of one or both breasts, either partially of fully. An oophorectomy is the surgical removal of an ovary or ovaries.

Biology
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BRCA1 mutation BRCA2 mutation No BRCA mutation Total Number of patients 89 35 318 442 Average age at diagnosis 43.9 46.2 50.4 Preventative mastectomy* 6 3 14 23 Preventative oophorectomy* 38 7 22 67 Number of deaths 16 1 21 38 Percent died 18 2.8 6.9 8.6 *A mastectomy is the surgical removal of one or both breasts, either partially of fully. An oophorectomy is the surgical removal of an ovary or ovaries. Things to address in your summary essay: Describe how mutations lead to genetic variations. Which appears to be more dangerous: the BRC1 or BRC2 mutation? Analyze a woman’s risk of dying of cancer if she carries a mutated BRC1 gene. How do heredity and inheritance relate to the data presented in these charts? What data would you need to see in order to draw conclusions about the effectiveness of preventive surgeries? What does the age at diagnosis tell you about the mutation? Explain how breast-cancer genes are still present in the population, despite cancer-related surgeries and deaths.
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yes. im stuck on it and i have to do it quickly to get my flvs done.
which part are you stuck on?
the whole thing... i have the chart but this is what it wants me to do Describe how mutations lead to genetic variations. Which appears to be more dangerous: the BRC1 or BRC2 mutation? Analyze a woman’s risk of dying of cancer if she carries a mutated BRC1 gene. How do heredity and inheritance relate to the data presented in these charts? What data would you need to see in order to draw conclusions about the effectiveness of preventive surgeries? What does the age at diagnosis tell you about the mutation? Explain how breast-cancer genes are still present in the population, despite cancer-related surgeries and deaths.
BRCA1 mutation BRCA2 mutation No BRCA mutation Total Number of patients 89 35 318 442 Average age at diagnosis 43.9 46.2 50.4 Preventative mastectomy* 6 3 14 23 Preventative oophorectomy* 38 7 22 67 Number of deaths 16 1 21 38 Percent died 18 2.8 6.9 8.6
you need to do some research yourself first, i mean the first question you can basically google. the second, just compare the data and see which percentage has the higher mortality rate the third, just see what the percentage of deaths for the BRC1 mutation there were in the study etc
ok. thanks
no problem, good luck.

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