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anonymous

  • one year ago

Okay I have a question, so I have two different colored eyes also known as heterochromia iridum and I was wondering what are the chances of my children having two different colored eyes? A lot of websites say its hereditary but is it something that skips a generation or? I don't know. I am just curious of the likelihood of my future children having this mutation?

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  1. shreehari499
    • one year ago
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    Hmm..Hey! @oliviacaroline2123 ! U there?

  2. shreehari499
    • one year ago
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    Anyways..the specific disease that you're speaking of is an Autosomal Dominant Trait

  3. shreehari499
    • one year ago
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    Is your husband Affected? or not ? so that i can draw the Pedigree Chart and find out the probability of your children being affected from it. :)

  4. anonymous
    • one year ago
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    @shreehair499 Lets say my nonexistent husband didn't have it, what would be the probability then? and thank you for helping me! :)

  5. shreehari499
    • one year ago
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    Consider you to be X^cX^c (affected) and your husband XY(normal)

  6. shreehari499
    • one year ago
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    C for heterochromatia iridium

  7. shreehari499
    • one year ago
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    So crossing X^cX^c with XY we get X^cX , X^cY , X^cX and X^cY

  8. shreehari499
    • one year ago
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    So this shows that both your daughters will not be affected, instead they will be carriers, buy both sons will be affected with the disease

  9. shreehari499
    • one year ago
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    *but

  10. anonymous
    • one year ago
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    @Shreeehari499 That kind of makes sense but also how does gender affect it?

  11. shreehari499
    • one year ago
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    Yeah gender does come into play... Suppose your husband is affected, the probability for all your children to be affected will be 100% I.e all boys and girls become affected

  12. anonymous
    • one year ago
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    You first said it was an autosomal dominant trait and then calculated probabilities as if it were a sex linked recessive trait? @shreehari499 Futhermore, it is not even always autosomal recessive, we need far more details to predict with reasonable accuracy anything about the offspring of @OliviaCaroline2123 It would be best for you if you talked about this to a genetic councelor now, or once you have a husband.

  13. Abhisar
    • one year ago
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    Hehe, as niel said it's not so simpe, \(Heterochromia~iridum\) is basically a class of disorder in which both eyes appear to have different color. It may be congenital or may be acquired. In case it is congenital, may be due to dominant, or in most cases may be a polygenic effect. it can also due to neurological disorders like in the case of weber syndrome.

  14. shreehari499
    • one year ago
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    *scratching head* Yeah right! I was wrong :)

  15. anonymous
    • one year ago
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    no problem

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