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1. Recognition of the AIDS epidemic in this country began in the late ‘70’s in SF, LA and NY. What clues, symptoms and opportunistic diseases were observed during that period that signaled the start of a new infectious disease? Why did researchers find these factors significant?
2. By the time the first HIV screening test was available in 1985, there were 8,408 reported cases of AIDS and 6,305 AIDS-related deaths in the US.
a. What was the cumulative incidence rate? What was the case-fatality rate?
b. Compare this to the cumulative incidence and fatality rates first reported in the movie and to 2012 incidence and fatality rates.
i. What would have happened if CDC had more support to investigate the initial outbreak?
ii. What changes in policy and medicine have improved the life span of HIV positive individuals?
3. Who is Gaten Dugas and why was he labeled as “patient 0”?”
a. How many sexual encounters did he have per year
b. What factors (personality, career) contributed to Gaten’s unique contribution to the AIDS epidemic.
4. Discuss some of the factors, including local and federal politics that inhibited the early war against AIDS.
5. List 2 examples of how patient confidentiality was or was not protected. How did access to patient names progress or inhibit the HIV investigation?
6. Describe the CDC’s approach to case investigations. Was active or passive surveillance used to identify the first AIDS cases?
7. Don Francis proposed using data (questionnaires and blood) from an existing study of Hepatitis B to inform the AIDS investigation. The study started before the AIDS epidemic, how would this help?